What is Rizatriptan 10 mg Orodispersible?

Rizatriptan 10 mg orodispersible tablets are a migraine treatment from a group of medicines called triptans. They are used to treat an acute migraine attack once it has started and can help reduce headache pain as well as associated symptoms such as nausea, sensitivity to light and sensitivity to sound.

This product page refers to rizatriptan 10 mg orodispersible tablets supplied on a private prescription following an online consultation.

How does Rizatriptan work?

Rizatriptan works by acting on serotonin receptors in blood vessels and nerves involved in migraine. This helps reverse the changes linked to a migraine attack and can reduce headache pain and other migraine symptoms. It is used to treat an attack that has already started and is not used to prevent migraines from happening.

What is Rizatriptan 10 mg Orodispersible used for on this page?

On this product page, rizatriptan 10 mg orodispersible tablets are used specifically for:

– Acute migraine attacks in adults

– Migraine with or without aura

– Relief of migraine headache and associated symptoms such as nausea, photophobia and phonophobia

It is not used here for:

– Migraine prevention

– Headaches that have not been diagnosed as migraine

– Hemiplegic migraine or basilar migraine

– Cluster headache unless specifically assessed for suitability

– Children 

Your prescriber will confirm rizatriptan is appropriate based on your symptoms, migraine history, medical history and any other medicines you are using.

Who may be suitable for Rizatriptan?

You may be suitable if:

– You are an adult with a clear history of migraine

– Your headaches fit a migraine pattern and are appropriate for triptan treatment

– You are able to use the orodispersible tablet as soon as the migraine headache starts

– You understand that it is for treating an attack rather than preventing future attacks

Your prescriber will consider:

– Your migraine history and whether the diagnosis is clear

– Whether your symptoms are typical of migraine or whether there are warning signs needing further assessment

– Whether you have heart disease, stroke risk factors, circulation problems or uncontrolled blood pressure

– Whether you take propranolol, as this can affect dosing

– Any other medicines or health conditions you have before deciding if rizatriptan is suitable for you.

Who should not use Rizatriptan 10 mg Orodispersible or needs medical advice first?

Do not use without medical advice if you:

– Are allergic to rizatriptan or any of the ingredients in the tablets

– Have coronary heart disease, previous heart attack, angina or significant heart rhythm problems

– Have had a stroke or transient ischaemic attack

– Have peripheral vascular disease

– Have uncontrolled high blood pressure

– Have severe liver impairment or severe kidney impairment unless specifically assessed

– Have been diagnosed with hemiplegic or basilar migraine

– Are taking ergotamine, methysergide or another triptan too close to the dose

– Are taking monoamine oxidase inhibitors or have taken them in the last 2 weeks

Use with caution and seek prescriber advice if you:

– Have risk factors for heart disease such as smoking, high cholesterol, diabetes or strong family history

– Have mild to moderate liver or kidney problems

– Are taking propranolol, because a lower dose is normally used

– Have epilepsy or a history of seizures

– Are taking SSRIs, SNRIs or other medicines that may increase the risk of serotonin syndrome

– Are pregnant or breastfeeding and want to check suitability first

How do I take Rizatriptan 10 mg Orodispersible?

Your prescriber will confirm the exact directions. A commonly used adult dosing schedule for migraine is:

– One 10 mg orodispersible tablet as soon as the migraine headache starts

Practical advice:

– It is best taken after the headache has started, rather than during the aura phase

– Place the tablet on your tongue and allow it to dissolve before swallowing

– You do not need water to take the orodispersible tablet

– If the first tablet helps but the migraine returns, a second dose may be taken after at least 2 hours if advised

– Do not take more than 2 doses in 24 hours

– If you take propranolol, the 10 mg strength is usually not suitable and a lower dose is normally used instead

If your symptoms get worse, do not improve as expected, or you develop new or unusual neurological symptoms, seek medical advice.

General self-care advice:

– Rest in a dark, quiet room if possible

– Keep hydrated

– Avoid driving if migraine symptoms or treatment side effects affect you

– Keep a migraine diary if attacks are frequent

– If you need migraine treatment often, ask for review because regular use can sometimes lead to medication overuse headache

Side effects and when to get help

Common side effects can include dizziness, tiredness, drowsiness, nausea and tingling sensations. These are often short-lived.

Seek medical advice urgently if you develop chest pain, severe shortness of breath, severe allergic symptoms, weakness on one side, trouble speaking, seizures, collapse or any severe unexpected reaction after taking the medicine.

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