Epiduo Gel 2.5% – Acne Cream

  • Effective Antibiotic-Free Acne Cream
  • Active Ingredients: Adapalene And Benzoyl Peroxide
  • See Improvement Within 1-4 Weeks
  • Buy Online From UK Registered Pharmacy
  • Includes Free Prescription



Buy Epiduo Gel Online UK

My Pharmacy offers the best place to buy Epiduo gel online UK with next day delivery available within the UK. To purchase Ventolin Epiduo gel, you will need a prescription, which is available through our free online consultation service. Each item you purchase will be sent via secure and discreet packaging to ensure that you receive your medicine in a complete and efficient manner.

What is Epiduo Gel?

Epiduo is a treatment for mild to moderate acne which can be used by patients as young as nine years old. It contains two active ingredients- Adapalene and Benzoyl peroxide which simultaneously to help reduce the acne that is present and prevent any occurring in the future. They improve the level of inflammation, which helps people who tend to get red, inflamed pimples. Adapalene is a retinoid which acts specifically on the skin process that causes acne. It helps shed dead skin cells and unblock pores to stop blemishes from reoccurring. Benzoyl peroxide is known as an antimicrobial which fights the bacteria that cause acne outbreaks.

We are often asked “What Epiduo Gel?”

As both ingredients work so effectively together, it can reduce the amount of treatment you may need to re-purchase. When the specific amount is used on the affected area, refills will only be required once every three months.

Epiduo is currently only available via prescription however the active ingredients contained within the gel (Adapalene & Benzoyl peroxide) can be purchased over the counter and as prescription medications.

How Long does it take for Epiduo Gel to work?

The amount of time it takes for Epiduo 2.5 gel to show results is usually between eight to twelve weeks. If you do not see any improvement in this time it is advised to discontinue this treatment and seek an alternative.

Once you have started treatment, you may experience an initial flare-up which is normal and can usually make the skin worse before improving. This flare-up can last up to four weeks before improvement. This occurs because the gel is bringing any current debris on the skin to come to the surface. This should not happen after eight weeks of continued use.

After eight weeks of using the gel, your skin should be showing signs of improvement however if this does not happen, please consult your doctor or dermatologist.

How Long Does it Take for Epiduo Gel to Work?

How long does it take for Epiduo Gel to work? Once treatment has been started, you may notice an initial flare-up, this is common and can usually go worse before improving. The flare-up can last up four weeks before improving.

This happens because the gel is making any current debris on the skin rise to the surface, this is usually not the case after eight weeks of the continued appliance.

After the eight week mark, your skin should be showing signs of improvement, if this isn’t the case, consult with your doctor or dermatologist.

Epiduo Gel How to Apply

Below is an overview on how to use Epiduo gel- for a further in-depth guide please refer to the patient information leaflet for additional guidelines. If you are unsure of any of the information, please consult your doctor or pharmacist.

  • apply a pea-sized amount over clean and dry skin, once a day at bedtime- avoid the eyes, lips and nostrils.
  • After using Epiduo gel, wash your hands thoroughly.

Duac Gel or Epiduo Gel

Differences between Duac Gel and Epiduo Gel

One of the biggest differences people notice is the significant increase in dryness of using Epiduo which causes higher volumes of water loss on the skin compared to using Duac. Some users also experienced mild burning and stinging when using Epiduo gel compared to Duac Gel.

Another difference is both products contain changed active ingredients with Epiduo gel containing Adapalene and Benzoyl peroxide, whilet Duac Gel contains Clindamycin and Benzoyl peroxide.

Clindomycin works by slowing down and/or stopping the growth of bacteria and is used to treat certain types of bacterial infections, including those on the skin.

In regards to common side effects , there are not many differences between the two medications.

Epiduo Acne Gel Side Effects

Here are some of the differences between Duac Gel and Epiduo Gel –

One of the first differences a lot of people notice is the significant increase in dryness when using Epiduo compared to Duac, with the former causing higher volumes of evaporative water loss on the skin.

Users testing the difference between the two also noted a higher frequency of adverse perceptions, including mild burning and stinging when using Epiduo Gel compared to Duac Gel.

Overall the two of them barely have any significant differences between them when comparing common side effects.

Another difference is that both uses changed active ingredients. Epiduo gel contains Adapalene and Benzoyl peroxide, whilst Duac Gel contains Clindamycin and Benzoyl peroxide. Clindamycin works by slowing or stopping the growth of bacteria, treating certain types of bacterial infections, including the skin.


Epiduo Acne Gel Side Effects

Like with all medicine, Epiduo 2.5 gel can have side effects, but these aren’t experienced by everyone.

Stop using this product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing. The frequency at which these side effects occur is not known. This could mean you have an adverse allergic reaction to the medicine.

Some of the common side effects include –



Skin irritation

Burning sensation

Dry skin

Skin rash

Uncommon side effects include –

Itchy skin


For more information on the side effects of Epiduo Gel, please consult the patient information leaflet located here.

Alternatives to Epiduo Gel 30g

My Pharmacy UK is the best place to Buy Epiduo Gel UK.

If Epiduo isn’t viable for you, here are some alternatives to Epiduo Gel 30g –

Duac Gel

Zineryt Solution 30ml

Oxytetracycline Tablets

Differin Cream

Additional information


1 Pack, 2 Pack